2021-09-24 08:12 There is structural information of ligand and receptor proteins. Generally, pharmacophore models represent key features of small molecules that allow them to bind-some receptor molecules, but this idea can be reversed, and pharmacophore queries are c ... дальше
2021-09-24 08:12 The pharmacophore model is very suitable as a search for a virtual screening database. However, one of the more common methods in virtual screening is the layered method, in which different methods are continuously combined, also known as the funnel ... дальше
2021-09-24 08:11 The pharmacophore model contains multiple functions of a specific 3D model. Each feature is usually represented as a sphere (despite changes), and the radius determines the deviation tolerance from the precise position. These functions can be marked ... дальше
