2021-09-24 08:12
There is structural information of ligand and receptor proteins. Generally, pharmacophore models represent key features of small molecules that allow them to bind-some receptor molecules, but this idea can be reversed, and pharmacophore queries are c
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2021-09-24 08:12
The pharmacophore model is very suitable as a search for a virtual screening database. However, one of the more common methods in virtual screening is the layered method, in which different methods are continuously combined, also known as the funnel
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2021-09-24 08:11
The pharmacophore model contains multiple functions of a specific 3D model. Each feature is usually represented as a sphere (despite changes), and the radius determines the deviation tolerance from the precise position. These functions can be marked
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