2021-05-19 09:19 Animal models are useful if they reproduce all or some of the clinical features of a disease. In systemic lupus erythematosus studies and preclinical tests of new therapeutics, spontaneous mouse models, as well as induced SLE models are commonly used based on different research requirements. Unlike NZB/W or MRL/lpr mouse models, in which genetic factors play a central role, induced mouse models develop lupus due to exposure to certain environmental triggers.
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