2020-10-31 16:10 Hantaan virus (HTNV) infection is an important cause of hemorrhagic fever with renal syndrome (HFRS) in Eurasia and of hantavirus pulmonary syndrome in the Americas. About 200,000 clinical cases of hantavirus disease are reported every year. Usually, HFRS occurs in 5 consecutive stages: febrile, hypotensive, oliguric, diuretic, and convalescent. Clinical symptoms also include thrombocytopenia and, in severe cases, bleeding due to capillary leak syndrome. HTNV is transmitted to humans by inhalation of aerosols extracted from rodent excreta. Its natural hosts are various small mammals, including rodents, shrews, moles, and bats.
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