2020-12-21 20:40 A single nucleotide polymorphism (SNP) represents a variation in a single nucleotide that occurs at a specific position in the genome. SNPs are the major contributors to the DNA variations among individuals, at a frequency of approximately one in 1,000 bp. SNPs have been suggested to be responsible for phenotypic differences, and to affect the development and progression of multiple diseases, as well as to determine the response of drug treatment and/or environmental stress. Additionally, SNPs can serve as ideal molecular markers for identifying genes associated with important biological characters and diseases. Therefore, SNP profiling is considered of great importance in selective breeding, agricultural production and productivity, personalized medicine and drug treatment.
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