2021-04-02 06:17"Based on years of abundant experience in the in vitro diagnostics (IVD) antibodies development, Creative Biolabs provides a variety of high quality IVD antibodies custom development service of miR-328 marker for the diagnosis of myocardial infarction (MI) and glioma.
MicroRNAs (miRNAs), endogenous, small noncoding RNA molecules, play important roles in the posttranscriptional inhibition through binding to 3'-UTRs of target mRNAs, leading to mRNA degradation and/or translational suppression. They are ubiquitously expressed in diverse of organisms and are evolutionary conserved. Former researches have demonstrated a pivotal role of miRNAs in many biological processes, such as proliferation, cell differentiation, cancers, and cardiovascular diseases. Besides, miRNAs are superior candidate biomarkers for a variety of diseases, due to their excellent features. For example, a majority of miRNA species are extremely stable and readily detectable in the peripheral blood, and the levels of circulating miRNAs are typically changed in individuals with various pathological situations. Candidate biomarkers for AMI should show cardiac-specific expression patterns, and some researches have assessed the diagnostic value of cardiac-enriched miRNAs in the setting of AMI."