2021-04-02 06:21 Advances in recombinant DNA technology, genomics and immunology have greatly affected the vaccine development process. The genetic manipulation of microbes makes them suitable as vectors for gene delivery, providing a unique opportunity for vaccine design. With the in-depth study of various microbes, viral vectors are becoming an important immuno-prophylactic tool in modern medical arsenals. Among various vaccine vectors, adenovirus vectors are being extensively investigated and show great promise as vaccine vectors.