2021-11-19 18:15 Polyglutamic acid (PGA) is polymer with good biocompatibility and complete degradability. Its safety has been approved by FDA of the United States, and it has been widely used in the field of medical and medicinal polymer materials
2021-11-19 18:15 NH2-PEG-(γ)PGA (amino-polyethylene glycol-poly-L-glutamic acid) is a linear amphiphilic block copolymer with poly-L-glutamate as hydrophobic part and amino group functionalized PEG as hydrophilic part.
2021-11-19 18:14 Methoxy polyethylene glycol (peg) poly-L-glutamic acid (mPEG–(γ)PGA) is a kind of diblock copolymer. mPEG–(γ)PGA can serve as the carrier materials of different kinds of drugs
2021-11-19 18:14 It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing.
2021-11-19 18:14 It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.
2021-11-19 18:13 2'-DeoxypseudoUridine belongs to the C-glycosides that linked by C-C bond rather than usual C1-N1 bond found in uridine. Especially, glycosidic bond of 2'-deoxypseudoUridine is that C-C bond between C5 of uracil and C1 of the deoxyribose sugar