2021-10-21 20:49
PROTAC ERRalpha Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRalpha Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader.

2021-10-21 20:48
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1,

2021-10-21 20:48
PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader.

2021-07-17 06:46
Molecular docking is an effective method to study protein-ligand interaction and recognition.

2021-07-17 06:46
Ubiquitin (UB) is a protein modifier that regulates many important cellular processes

2021-07-17 06:46
E3 ubiquitin ligase is an enzyme that specifically binds to PROTAC®,

2021-07-17 06:46
Ubiquitin ligase, also known as E3 ubiquitin ligase, is an enzyme that connects ubiquitin molecules to a lysine of the target protein

2021-07-17 06:46
Among the natural protein degradation cascades, the ubiquitin-proteasome (UP) cascade is most characteristic.

2021-07-17 06:46
Molecular glue is a kind of small chemical molecules that act on the interface between protein and protein.