2022-01-29 23:13
Molecular glue; induces proteosomal degradation of mRNA splicing factor RBM39.

2022-01-29 23:12
E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker.

2022-01-29 23:12
E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase,

2022-01-29 23:12
E3 ligase Ligand-Linker Conjugates 14 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

2021-12-19 19:27
cIAP1 ligand 2 is the LCL161 derivative based IAP ligand. cIAP1 ligand 2 can be connected to the ABL ligand for protein by a linker to form SNIPER.

2021-12-19 19:27
cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. cIAP1 ligand 1 can be connected to the ABL ligand for protein by a linker to form SNIPER.

2021-12-19 19:27
c-diGMP is a bacterial second messenger and a STING ligand.

2021-12-19 19:26
Boc-C5-O-C5-O-C6-Cl is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.

2021-10-21 20:49
PROTAC ERRalpha Degrader-2 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group.