2021-11-19 18:14 It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.
2021-11-19 18:13 2'-DeoxypseudoUridine belongs to the C-glycosides that linked by C-C bond rather than usual C1-N1 bond found in uridine. Especially, glycosidic bond of 2'-deoxypseudoUridine is that C-C bond between C5 of uracil and C1 of the deoxyribose sugar
