2021-07-21 11:59 Sumoylation is a classic protein post-translational modification biotechnology in protein drug development and production. Sumoylation Analysis can be used for enriching modified peptides, analyzing peptide mass spectra, identifying modification site ... дальше
2021-07-21 11:36 The three-dimensional structure of a protein provides basic information about its biological function and helps design therapeutic drugs that specifically bind to protein targets. In recent years, the number of experimentally determined protein struc ... дальше
2021-07-21 10:58 Negative stain electron microscopy (EM) is a technology that provides nanometer-resolution images of biological macromolecules. At present, the main role of negative stain EM in protein structural analysis is to construct an initial model and to cond ... дальше
2021-07-21 10:47 Natural MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three identical peptide chains of 32 kDa each. Although MBL can form several oligomeric forms, there are indications that dimers and trimers are not biologically ac ... дальше
2021-06-28 19:31 Post-transcriptional regulation contributes to the ability of cells to modify gene expression when facing changing external or internal environment.
2021-06-28 19:10 Ubiquitin refers to the process in which ubiquitin molecules classify intracellular proteins under the action of a series of special enzymes,
2021-06-27 20:35 The ongoing outbreak of novel coronavirus (also termed as SARS-CoV-2) poses a challenge for public health. There is an urgent need to understand the molecular mechanism of this viral infection and to develop effective vaccines and antiviral drugs on ... дальше
2021-06-27 19:50 In order to assess the biological function of proteins for understanding signaling mechanisms within cells as well as specific biomarkers to disease, it is vital to study the difference of proteome under different experimental conditions. The new eme ... дальше
2021-06-27 19:49 Protein purity and homogeneity are key for protein crystallization and rigorous structural and functional studies. Impure samples will lead to inaccurate and imprecise results across experiments. In addition, Protein purity and homogeneity are two ve ... дальше